GOJI-BEERE
Aktuelle wissenschaftliche Studien | 96-115
96: Biomed Environ Sci. 2003 Sep;16(3):267-75.
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Inhibiting effects of Achyranthes bidentata polysaccharide and Lycium barbarum polysaccharide on nonenzyme glycation in D-galactose induced mouse aging model.
Deng HB, Cui DP, Jiang JM, Feng YC, Cai NS, Li DD.
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
OBJECTIVE: To investigate the inhibiting effects and mechanism of achyranthes bidentata polysaccharide (ABP) and lycium barbarum polysaccharide (LBP) on nonenzyme glycation in D-galactose induced mouse aging model. METHODS: Serum AGE levels were determined by AGE-ELISA, MTT method was used to determine lymphocyte proliferation, IL-2 activity was determined by a bioassay method. Spontaneous motor activity was used to detect mouse's neuromuscular movement, latency of step-through method was used to examine learning and memory abilities of mouse, colormetric assay was used to determine hydroxyproline concentration in mouse skin, pyrogallol autoxidation method was used to determine superoxide dismutase (SOD) activity of erythrocytes. RESULTS: Decreased levels of serum AGE, hydroxyproline concentration in mouse skin and spontaneous motor activity in D-galactose mouse aging model were detected after treated with ABP or LBP, while lymphocyte proliferation and IL-2 activity, learning and memory abilities, SOD activity of erythrocytes, were enhanced. CONCLUSIONS: ABP and LBP could inhibit nonenzyme glycation in D-galactose induced mouse aging model in vivo and ABP has a better inhibiting effect than LBP.
Publication Types:
PMID: 14631832 [PubMed - indexed for MEDLINE]
97: J Agric Food Chem. 2003 Nov 19;51(24):7044-9.
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Identification and quantification of zeaxanthin esters in plants using liquid chromatography-mass spectrometry.
Weller P, Breithaupt DE.
Universität Hohenheim, Institut für Lebensmittelchemie, Garbenstrasse 28, D-70599 Stuttgart, Germany.
It has been suggested that lutein and zeaxanthin may decrease the risk for age-related macular degeneration. Surprisingly, oleoresins rich in zeaxanthin are not yet available on the market. Several authors have reported enhanced stability of esterified xanthophylls, so plants containing zeaxanthin esters were investigated to establish valuable sources for the production of durable oleoresins. Liquid chromatography-atmospheric pressure chemical ionization mass spectrometry [LC-(APCI)MS] was used to unequivocally identify zeaxanthin esters of a standard mixture and in several plant extracts. Zeaxanthin esters were quantified on the basis of their respective molecular masses using zeaxanthin for calibration; total zeaxanthin was determined after saponification of aliquots of the extracts. Thus, dried wolfberries (Lycium barbarum), Chinese lanterns (Physalis alkekengi), orange pepper (Capsicum annuum), and sea buckthorn (Hippophae rhamnoides) proved to be valuable zeaxanthin ester sources. The present LC-MS method allows for an even more detailed analysis of zeaxanthin esters than reported previously.
Publication Types:
PMID: 14611169 [PubMed - indexed for MEDLINE]
98: Nutrition. 2003 Oct;19(10):869-75.
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In vitro analysis of the properties of Beiqishen tea.
Blázovics A, Szentmihályi K, Lugasi A, Balázs A, Hagymási K, Bányai E, Then M, Rapavi E, Héthelyi E.
II Department of Medicine, Semmelweis University, Budapest, Hungary. blaz@bel2.sote.hu
OBJECTIVE: Chinese Beiqishen tea was studied in an in vitro test system. METHODS: Phytochemical screening, trace element analysis, and the analysis of antioxidant properties were carried out. Characteristic constituents were determined by chromatographic (capillary gas chromatography and GCQ Ion Trap mass spectrometry) and spectrometric (ultraviolet and UV-VIS) methods. Element concentrations were determined by inductively coupled plasma optical emission spectrometry. Antioxidant capacity was studied by spectrophotometric and luminometric techniques using a Berthold Lumat 9501 luminometer. Hydrogen-donating activity, reducing power, and total scavenger capacity were measured. RESULTS: Total polyphenol content was 20.77 +/- 0.52 g/100 g of drug; total flavonoid content was 0.485 +/- 0.036 g/100 g of drug; and tannin content was 9.063 +/- 0.782 g/100 g of drug. Caffeine content was 1.08 mg/100 g of drug. Essential oils were identified by gas chromatography: (+)-limonene (21%), p-cymene (1.7%), estragol (3.2%), beta-ocimene (1.4%), and thymol (2.6%). Metallic ion analysis showed significantly high concentrations of Al, As, Ba, Cr, Cu, Fe, Mn, Ni, and Ti in the drug. Antioxidant and scavenger properties were identified as a function of concentration. CONCLUSIONS: The tea infusion contained some non-desirable trace elements and caffeine in addition to polyphenols and tannins in high concentrations. Therefore, the consumption of this tea may involve risks.
Publication Types:
PMID: 14559323 [PubMed - indexed for MEDLINE]
99: Ann Bot (Lond). 2003 Dec;92(6):757-65. Epub 2003 Oct 8.
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Photosynthetic responses of the tropical spiny shrub Lycium nodosum (Solanaceae) to drought, soil salinity and saline spray.
Tezara W, Martínez D, Rengifo E, Herrera A.
Centro de Botánica Tropical, Instituto de Biología Experimental, Universidad Central de Venezuela, Apartado 47577, Caracas 1041-A, Venezuela. wtezara@strix.ciens.ucv.ve
Water relations and photosynthetic characteristics of plants of Lycium nodosum grown under increasing water deficit (WD), saline spray (SS) or saline irrigation (SI) were studied. Plants of this perennial, deciduous shrub growing in the coastal thorn scrubs of Venezuela show succulent leaves which persist for approx. 1 month after the beginning of the dry season; leaf succulence is higher in populations closer to the sea. These observations suggested that L. nodosum is tolerant both to WD and salinity. In the glasshouse, WD caused a marked decrease in the xylem water potential (psi), leaf osmotic potential (psi(s)) and relative water content (RWC) after 21 d; additionally, photosynthetic rate (A), carboxylation efficiency (CE) and stomatal conductance (gs) decreased by more than 90 %. In contrast, in plants treated for 21 d with a foliar spray with 35 per thousand NaCl or irrigation with a 10 % NaCl solution, psi and RWC remained nearly constant, while psi(s) decreased by 30 %, and A, CE and gs decreased by more than 80 %. An osmotic adjustment of 0.60 (SS) and 0.94 MPa (SI) was measured. Relative stomatal and mesophyll limitations to A increased with both WD and SS, but were not determined for SI-treated plants. No evidence of chronic photoinhibition due to any treatment was observed, since maximum quantum yield of PSII, Fv/Fm, did not change with either drought in the field or water or salinity stress in the glasshouse. Nevertheless, WD and SI treatments caused a decrease in the photochemical (qP) and an increase in the non-photochemical (qN) quenching coefficients relative to controls; qN was unaffected by the SS treatment. The occurrence of co-limitation of A by stomatal and non-stomatal factors in plants of L. nodosum may be associated with the extended leaf duration under water or saline stress. Additionally, osmotic adjustment may partly explain the relative maintenance of A and gs in the SS and SI treatments and the tolerance to salinity of plants of this species in coastal habitats.
Publication Types:
PMID: 14534200 [PubMed - indexed for MEDLINE]
100: Zhong Yao Cai. 2003 Jun;26(6):391-4.
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[Investigation on occurrence of lycium barbarum pests and its natural enemies at Ningxia]
[Article in Chinese]
Chen J, Cheng H, Zhang J, Zhang G, Ding W.
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094.
OBJECTIVE: To provide the scientific basis for controlling Lycium barbarum pests. METHODS: The kinds and number of the pests and its natural enemies were investigated at fixed plants. RESULT: There were 38 species of Lycium barbarum pests and 23 species of natural enemies, the occurrence of them were closely related. CONCLUSION: Natural enemies can control Aphis and Paratrioza effectively.
Publication Types:
PMID: 14528676 [PubMed - indexed for MEDLINE]
101: Guang Pu Xue Yu Guang Pu Fen Xi. 2001 Dec;21(6):846-8.
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[Determination of iron(II) in the Chinese herbal medicine based on the fluorescence quenching of phenanthroline]
[Article in Chinese]
Aodeng GW, Bai WY, Duan ZQ.
Institude of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China.
A new spectrofluorimetric method for the determination of trace amounts of iron(II) has been developed. This method is based on the fluorescence quenching of phenanthroline due to the formation of complex Fe(II)-phen. In pH = 4.6-7.1 buffer solution, Fe(II) and phen react to form a red complex. Its composition is established by method of continuous variations and molar-ratio as Fe (II): phen = 1:2. The exitation and emission wavelength are found to be 265 nm and 365 nm, respectively. There is a linear relationship in the range of 24-112 ng.mL-1 for Fe(II). The detection limit of Fe(II) is 4.1 ng.mL-1. This method is simple and rapid, and has been applied to the determination of iron in the chinese herbal medicine.
Publication Types:
PMID: 12958912 [PubMed - indexed for MEDLINE]
102: Guang Pu Xue Yu Guang Pu Fen Xi. 2001 Dec;21(6):787-9.
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[A rapid method for the identification of four different features of gouqizi by FTIR spectrometry]
[Article in Chinese]
Sun SQ, Wang MQ, Leung HW, Yeung HW.
Department of Chemistry, Tsinghua University, Beijing 100084, China.
In this article, a method of using Fourier-transform infrared (FTIR) spectrometry to identify four Lyeium barbarum L. (Gouqizi) in turn of colour, shape, taste and water content. The four features (include color is red or black, shape is round or long, quality is dry or wet, taste is sweet or bitter) are related with the FTIR absorption peaks, this is based on the chemical components and their relative contents are different in various Gouqizi. These differences can be reflected in the FTIR spectra. So a new idea is brought up in the research area of identification of traditional Chinese medicine. Alao, FTIR is proved to be a rapid, simple, reliable and non-destructive qualification method.
Publication Types:
PMID: 12958895 [PubMed - indexed for MEDLINE]
103: Chang Gung Med J. 2003 Jun;26(6):449-52.
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Pregnancy in premature ovarian failure after therapy using Chinese herbal medicine.
Chao SL, Huang LW, Yen HR.
Department of Gynecology and Pediatrics, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan.
We present ovulation that occurred after the administration of traditional Chinese herbal medicine for 3 months in a woman with premature ovarian failure (POF) and secondary amenorrhea for 8 years. Traditional Chinese medicine concentrated herbal extracts of cooked rehmannia, Chinese yam, wolfberry fruit, dogwood fruit, cyathula root, dodder seed, antler glue, tortoise-plastron glue, epimedium and morinda root were prescribed, which were a modification of the herbal formula Zuo-gui-wan. When the patient discontinued the Chinese herbal medicine treatment and tried therapy with clomiphene citrate, neither ovulation nor conception occurred. Eight months after beginning clomiphene citrate therapy, the concentrations of follicle stimulating hormone and luteinizing hormone were still in the postmenopausal range. The modified formula of Zuo-gui-wan was prescribed again and the patient conceived 1 month after taking Zuo-gui-wan. Thus, we suggested that Chinese herbal medicine restored ovarian function effectively and promptly, and offers another option for treating infertility in patients with POF.
Publication Types:
PMID: 12956293 [PubMed - indexed for MEDLINE]
104: Guang Pu Xue Yu Guang Pu Fen Xi. 2003 Jun;23(3):509-11.
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[FTIR and classification study on gouqi from different cultural areas]
[Article in Chinese]
Zhou Q, Sun SQ, Leung HW.
Department of Chemistry, Tsinghua University, Beijing 100084, China.
Gouqi, a commonly used traditional Chinese medicine, was studied by Fourier transform infrared (FTIR) spectroscopy in this paper. The combination of FTIR with mathematic method was used for the first time to classify the Gouqi from different cultural areas. It can be seen that the Gouqi samples from Ningxia Yuxi, Ningxia Zhongning and Neimenggu Tuoketuoqi could be successfully classified by soft independent modeling of class analogy (SIMCA). As having the fast and accurate characters, FTIR provides a new way to evaluate the origin of the Chinese medicines impersonally based on the traditional methods.
Publication Types:
PMID: 12953527 [PubMed - indexed for MEDLINE]
105: Zhong Yao Cai. 2000 May;23(5):295-8.
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[Advances in immunopharmacological study of Lycium barbarum L.]
[Article in Chinese]
Xu Y, He L, Xu L, Liu Y.
Department of Pharmacy, Zhongshan University, Guangzhou, 510275
Publication Types:
PMID: 12934598 [PubMed - indexed for MEDLINE]
106: Eur J Pharmacol. 2003 Jun 27;471(3):217-22.
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A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells.
Gan L, Zhang SH, Liu Q, Xu HB.
Institute of Pharmacy, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China. ganlu07@163.com
The production of cytokine is a key event in the initiation and regulation of an immune response. Many compounds are now used routinely to modulate cytokine production, and therefore the immune response, in a wide range of diseases, such as cancer. Interleukin-2 and tumor necrosis factor-alpha are two important cytokines in antitumor immunity. In this study, the effects of Lycium barbarum polysaccharide-protein complex (LBP(3p)) on the expression of interleukin-2 and tumor necrosis factor-alpha in human peripheral blood mononuclear cells were investigated by reverse transcription polymerase chain reaction (RT-PCR) and bioassay. Administration of LBP(3p) increased the expression of interleukin-2 and tumor necrosis factor-alpha at both mRNA and protein levels in a dose-dependent manner. The results suggest that LBP(3p) may induce immune responses and possess potential therapeutic efficacy in cancer.
Publication Types:
PMID: 12826241 [PubMed - indexed for MEDLINE]
107: Drug News Perspect. 2001 Aug;14(6):353-63.
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Herbal preparations as a source of hepatoprotective agents.
Ram VJ.
Medicinal Chemistry Division, Central Drug Research Institute, Lucknow, India.
Mono- and polyherbal preparations with potent antihepatotoxic activity in various liver disorders, made from traditionally used herbs with proven efficacy, have been described. More than 700 mono- and polyherbal preparations in the form of decoction, tincture, tablets and capsules from more than 100 plants are in clinical use. Some of the herbs--such as Silybum marianum, Picrorhiza kurroa, Andrographis paniculata and Glycyrrhizae radix--are very common in most of the polyherbal preparations. This review covers the preparations of widely used herbs such as S. marianum, Schisandra chinensis, Phyllanthus amarus, P. kurroa, A. paniculata, G. radix, Lycium chinense and Cochlospermum tinctorium as hepatoprotectants and includes the mode of action of these preparations. Some polyherbal preparations such as Livex, HD-03, Hepatomed and Hepatoguard with proven efficacy are also described in this review. (c) 2001 Prous Science. All rights reserved.
PMID: 12813598 [PubMed]
108: Zhongguo Zhong Yao Za Zhi. 2002 Nov;27(11):819-23.
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[Investigation on occurrence of lycium pests and their natural enemies]
[Article in Chinese]
Chen J, Cheng HZ, Ding WO, Zhang GZ, Du XG.
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China. junzichen@263.net
OBJECTIVE: To Provide the scientific basis for controlling the lycium pests. METHOD: The kinds and number of pests and their natural enemies were investigated at regular intervals and on the fixed trees. RESULT: There are 13 kinds of lycium pests and 17 kinds of natural enemies, the occurrence of which are closely related. CONCLUSION: Natural enemies can control aphids and psyllidae effectively, but ten-spotted lema and Epithrix sp. must be controlled by pesticides.
Publication Types:
PMID: 12776583 [PubMed - indexed for MEDLINE]
109: Zhongguo Zhong Yao Za Zhi. 2002 Mar;27(3):215-8.
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[Study on antiinflammatory effect of a compound TCM agent containing ant extractive in animal models]
[Article in Chinese]
Wei RB, Huo HR, Li XQ, Zhou AX, Shen H, Tian JL.
General Air Force Hospital of Chinese PLA, Beijing 100036, China.
OBJECTIVE: To study the antiinflammatory effect of a compound TCM (Traditional Chinese Medicine) agent on animal models. The agent contains ant extractive and a blent of three herbal products, herba epimedii, fructus cnidii, and fructus lycii. METHOD: Three animal models to induce experimental inflammation in rats, including carrageenin--induced paw edema, cotton-ball granuloma and adjuvant induced arthritis, were chosen to study the antiinflammatory effect of the TCM agent. RESULT: The TCM agent showed a marked inhibitory effect on edema induced by all three types of inflammation in rats, the inhibitory rate of the TCM agent at the dose of 0.20, 0.40 and 0.80 g.kg-1 in granuloma model bing over 25% at 1 hour post oral administration, and being 23.8%, 22.7%, 39.7% at 6 hour. In addition, the TCM agent also showed a significant preventive as well as therapeutic effect on adjuvant induced arthritis in rats, and improved the pathological changes of the animal joints with the induced arthritis. CONCLUSION: TCM agent has significant antiinflammatory effects on the three above mentioned animal models.
Publication Types:
PMID: 12774406 [PubMed - indexed for MEDLINE]
110: Wei Sheng Yan Jiu. 2000 Mar 30;29(2):115-7.
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[Isolation and purification of Lycium barbarum polysaccharides and its antifatigue effect]
[Article in Chinese]
Luo Q, Yan J, Zhang S.
Department of Hygiene, Hubei Medical University, Wuhan 430071, China.
A purified component of lycium barbarum polysaccharide (LBP-X) was isolated from lycium barbarum L. by DEAE ion-exchange cellulose and sephacryl gel chromatography. LBP-X was tested on five different doses (5, 10, 20, 50 and 100 mg.kg-1.d-1) in mice. The results showed that LBP-X induced a remarkable adaptability to exercise load, enhanced resistance and accelerated elimination of fatigue. LBP-X could enhance the storage of muscle and liver glycogen, increase the activity of LDH before and after swimming, decrease the increase of blood urea nitrogen (BUN) after strenuous exercise, and accelerate the clearance of BUN after exercise. The dosage of LBP-X 10 mg.kg-1.d-1 was the best amount among the five tested doses.
Publication Types:
PMID: 12725093 [PubMed - indexed for MEDLINE]
111: Oecologia. 2003 Mar;134(4):547-53. Epub 2003 Jan 25.
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Responses of soil nitrogen dynamics in a Mojave Desert ecosystem to manipulations in soil carbon and nitrogen availability.
Schaeffer SM, Billings SA, Evans RD.
601 Science and Engineering Building, University of Arkansas Stable Isotope Laboratory, University of Arkansas, Fayetteville 72701, USA. smschae@uark.edu
We investigated the effects of changes in soil C and N availability on N mineralization, nitrification, denitrification, NH(3) volatilization, and soil respiration in the Mojave Desert. Results indicate a C limitation to microbial N cycling. Soils from underneath the canopies of Larrea tridentata (DC.) Cov., Pleuraphis rigida Thurber, and Lycium spp. exhibited higher rates of CO(2 ) flux, lower rates of NH(3) volatilization, and a decrease in inorganic N (NH(4)(+)-N and NO(3)(-)-N) with C addition. In addition to C limitation, soils from plant interspaces also exhibited a N limitation. Soils from all locations had net immobilization of N over the course of a 15-day laboratory incubation. However, soils from interspaces had lower rates of net nitrification and potential denitrification compared to soils from under plant canopies. The response to changes in C availability appears to be a short-term increase in microbial immobilization of inorganic N. Under controlled conditions, and over a longer time period, the effects of C and N availability appear to give way to larger differences due to spatial location. These findings have implications for ecosystems undergoing changes in soil C and N availability due to such processes as desertification, exotic species invasions, or elevated atmospheric CO(2) concentration.
Publication Types:
PMID: 12647127 [PubMed - indexed for MEDLINE]
112: Evolution. 2003 Jan;57(1):74-86.
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Floral morphometrics and the evolution of sexual dimorphism in Lycium (Solanaceae).
Miller JS, Venable DL.
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721, USA. jsmiller@amherst.edu
Plants of Lycium californicum, L. exsertum, and L. fremontii produce flowers that are either male-sterile (female) or hermaphroditic, and populations are morphologically gynodioecious. As is commonly found in gynodioecious species, flowers on female plants are smaller than those on hermaphrodites for a number of floral traits. Floral size dimorphism has often been hypothesized to be the result of either a reduction in female flower size that allows reallocation to greater fruit and seed production, or an increase in hermaphroditic flower size due to the increased importance of pollinator attraction and pollen export for hermaphroditic flowers. We provide a test of these two alternatives by measuring 11 floral characters in eight species of Lycium and using a phylogeny to reconstruct the floral size shifts associated with the evolution of gender dimorphism. Our analyses suggest that female flowers are reduced in size relative to the ancestral condition, whereas flowers on hermaphrodites have changed only slightly in size. Female and hermaphroditic flowers have also diverged both from one another and from ancestral cosexual species in several shape characteristics. We expected sexual dimorphism to be similar among the three dimorphic taxa, as gender dimorphism evolved only a single time in the ancestor of the American dimorphic lineage. While the floral sexual dimorphism is broadly similar among the three dimorphic species, there are some species-specific differences. For example, L. exsertum has the greatest floral size dimorphism, whereas L. fremontii had the greatest size-independent dimorphism in pistil characters. To determine the degree to which phylogenetic uncertainty affected reconstruction of ancestral character states, we performed a sensitivity analysis by reconstructing ancestral character states on alternative topologies. We argue that investigations such as this one, that examine floral evolution from an explicitly phylogenetic perspective, provide new insights into the study of the evolution of floral sexual dimorphism.
Publication Types:
PMID: 12643569 [PubMed - indexed for MEDLINE]
113: Yao Xue Xue Bao. 2001 Mar;36(3):196-9.
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[Studies on the active polysaccharides from Lycium barbarum L.]
[Article in Chinese]
Duan CL, Qiao SY, Wang NL, Zhao YM, Qi CH, Yao XS.
AIM: To investigate the structures and immunomodulation activity of four homogeneous polysaccharides: LBP 1a-1, LBP 1a-2, LBP 3a-1 and LBP 3a-2 isolated from Lycium barbarum L. brought from Zhongning County, Ningxia Province. METHODS: Their molecular weights, sugar component (constituents) and their linkages were determined by gel permeation chromatography, acid hydrolysis, periodate oxidation and NMR spectrum. The activity of immunomodulation was evaluated with splenocyte proliferation by [3H]-TDR incorperation, in vitro. RESULTS: Four polysaccharides with molecular weights 11.5 x 10(4), 9.4 x 10(4), 10.3 x 10(4) and 8.2 x 10(4), were shown to enhance splenocyte proliferation induced by ConA. LBP 1a-1 and LBP 1a-2 were alpha-(1-->6)-D-glucans. LBP 3a-1 and LBP 3a-2 were found to be a-(1-->4)-D-polygalacturonans. CONCLUSION: The four polysaccharides were first isolated from this plant. Polysaccharides with main chain of alpha-(1-->4)-D-polygalacturonans showed stronger immunomodulation activity.
Publication Types:
PMID: 12580087 [PubMed - indexed for MEDLINE]
114: Yao Xue Xue Bao. 2001 Aug;36(8):599-602.
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[Physico-chemical properties and activity of glycoconjugate LbGp2 from Lycium barbarum L.]
[Article in Chinese]
Peng XM, Wang ZF, Tian GY.
Shanghai Institute of Organic Chemistry, State Key Laboratory of Bio-organic Chemistry, Academia Sinica, Shanghai 200032, China.
AIM: To isolate and purify a glycoconjugate (LbGp2) from the fruit of Lycium barbarum L. and study its immunoactivity and antioxidative activity. METHODS: By means of gel permeation chromatography, LbGp2 was purified. Based on HPLC, CE, GC, SEC and component analysis and so on, its physico-chemical properties were studied. RESULTS: Molecular weights of LbGp2 was 68.2 ku and its carbohydrate content was up to 90.7%. Component analysis showed that it composed of Ara and Gal in a molar ratio of 3:4, and 18 kinds of amino acids. The immunologic function and bioactivity of Lbp2 has been studied preliminarily. Lbp2 was shown to increase rate of phagocyticaction and phagocytic index, promote lymphocyte translation and accelerate the production of serum hemolysin. LbGp2 has distinct effect of antioxidation and the superoxide anion produced by DMSO-NaOH system was scavenged effectively. CONCLUSION: LbGp2 was shown to be a kind of homogeneous glycoconjugate with good immunoactivity and antioxidative activity.
Publication Types:
PMID: 12579937 [PubMed - indexed for MEDLINE]
115: Yao Xue Xue Bao. 2001 Feb;36(2):108-11.
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[Studies on the glycoconjugates and glycans from Lycium barbarum L in inhibiting low density lipoprotein (LDL) peroxidation]
[Article in Chinese]
Huang LJ, Tian GY, Wang ZF, Dong JB, Wu MP.
State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
AIM: To determine the effects of glycoconjugates and their glycans from Lycium barbarum L. on inhibiting low density lipoprotein (LDL) peroxidation. METHODS: Using Cu(2+)-induced oxidation as a model, the oxidative production of thiobarbituric acid-reactive substances (TBARS) and the LDL electrophoresis migration on agarose gel were measured. RESULTS: The effects of glycoconjugates and their glycans from Lycium barbarum L. on inhibiting LDL peroxidation were different, among them, glycoconjugate LbGp5 showed the best effect on inhibiting LDL peroxidation. CONCLUSION: The glycoconjugates can inhibit LDL peroxidatin while their glycans showed no effects on inhibiting LDL peroxidation.
Publication Types:
PMID: 12579875 [PubMed - indexed for MEDLINE]
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